Easy Like IHCby Assay Upp
Why Easy Like IHC?

A brand story from the bench.

Easy Like IHC began with something I did not understand about myself for a long time: IHC had always felt unusually natural to me. What took longer was realizing that “this feels obvious to me” is not the same thing as “this is obvious.”

01

IHC just made sense to me.

When I first learned IHC, I loved it. The workflow felt natural, the result was visible under the microscope, and I could usually tell very quickly whether something had worked.

I never thought of IHC as particularly difficult. Sure, antibodies could be tricky - but to me that was the fun part. You optimized them until they worked.

After a while, I could set up a staining almost any time of day without even having the protocol next to me. It was not that I had memorized every possible assay. The basic logic of the workflow simply clicked.

To me, it was just… easy.

02

Then the question became: how do I do more without making the workflow worse?

As my work grew, one staining run was no longer the whole problem. I wanted to run several sets of stains in a day, often with more than 20 slides at a time.

That changes the way you look at IHC. Suddenly you notice how much time is spent moving slides between steps, how easy it is to disturb their order, how evenly incubation times are applied across a batch, where the reagents sit, how many times you pick the same slide up, and whether the equipment around the assay is actually helping you.

The staining chemistry still mattered, of course. But I started thinking just as much about throughput, organization and repeatability.

That was probably the beginning of my obsession with the small practical details around an experiment.

03

A mentor pointed out something I had completely missed.

During my postdoc, I was thinking seriously about which skills I should develop for the next stage of my career. With my background in biomarker discovery, I told my mentor that I was considering specializing more in bioinformatics.

His answer surprised me.

“I always thought of you as an antibody-and-tissue type of girl. I think you do things with slides that others cannot.”

I was almost offended.

How could something as basic as IHC possibly be an asset? I could practically do it in my sleep.

04

It was never only about running an IHC protocol.

When I looked back at the work I had actually been doing, the pattern was much broader.

I was making difficult antibodies work. Optimizing staining across species. Running immunofluorescence and multiplex staining. Developing in situ hybridization when reliable antibodies did not exist. Combining RNA and protein targets. Building co-stains. Working with proximity-based assays, DNA-based readouts and spatial biology approaches for biomarker discovery and product development.

And I was often helping other scientists work out whether an unexpected staining pattern was biology, background or something technically wrong.

The assays became more sophisticated. But the same practical questions kept coming back: can this workflow be made clearer, more efficient and easier to repeat?

05

What finally clicked was the difference between “obvious to me” and “obvious.”

I had been confusing “this feels obvious to me” with “this is obvious.”

IHC had always made intuitive sense to me. I did not have to fight with the logic of the workflow; it simply clicked. Years of experience made me better and more sophisticated at it, but the foundation was there from the beginning.

I had assumed that because it felt easy to me, it must be easy for everyone.

It wasn’t.

And the same was true for the practical things around the assay. Good organization, sensible handling and the right little tool can feel completely obvious once they are in place - but that does not mean they happen automatically.

06

That is where Easy Like IHC came from.

Over the years, I accumulated a mental collection of tools that made laboratory work noticeably better: racks that kept samples organized, holders that reduced unnecessary handling, systems that made mix-ups less likely, and small pieces of equipment that simply made a workflow easier to repeat.

None of them were revolutionary.

Some were just really good racks.

But sometimes a simple rack can change your life - or at least your afternoon at the bench.

That is the idea behind Easy Like IHC.

I select and design practical laboratory tools that I would want to use myself, and I try to explain not only what they are, but why I find them useful and how they fit into a real laboratory workflow.

The goal is not to make biology simple. Biology is complicated enough.

The goal is to make the things around the biology a little easier - and perhaps help a few more laboratory workflows feel as natural and intuitive as IHC has always felt to me.

What this means in practice

Practical tools I would genuinely want on my own bench.

A small, growing collection selected or designed around real laboratory workflows - with scientific consulting when the problem needs a human tool rather than another piece of equipment.